The title for this one comes from those stupid "1 tip for a flat belly!" and "The thing moms know about whitening teeth!" ads that keep popping up for me. You know the ones. Well, now, screw that. WHAT'S more important than getting a flat belly or whitening your teeth?! CURING YOUR AGING NEUROMUSCULAR JUNCTIONS!!!
Scientists have been searching for the fountain of youth for ages. Not an actual fountain, or a cure for aging, but the REASON behind the declines and changing that come along with age. A few years ago, scientists found that exercise and a low calorie diet (VERY low calorie, not something that is maintained easily), can reduce the effects of aging and dramatically extend lifespan in rodents. The question is, though, HOW this happens.
Valdez, et al. "Attenuation of age-related changes in mouse neuromuscular synapses by caloric restriction and exercise" PNAS, 2010.
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It's the second to last day of SFN. Sci thought she was a grad student of boundless energy, but even she is beginning to feel...a little burned out. Posters, each one of the good and showing some seriously cool stuff, slide past her eyes. After a while you can barely remember what you just saw, even though you desperately want to, because you know you would never have seen it had it not been terribly cool. But at a conference this big, with so many people, it's hard to remain "on" all the time, to ask the brilliant questions, to give the perfect presentation.
But press on we must! SFN comes only once a year. It's like neuroscience Xmas! You have to soak in every inch of the experience. And even through your fog of exhaustion (and possibly your fog of hangover), there are some posters that stick out at you. Some that are elegant and interesting, no matter how tired you are:
*D. E. PANKEVICH, G. SMAGIN, T. L. BALE; Animal Biol, Univ. Pennsylvania, Philadelphia, PA; AstraZeneca, Wilmington, DE "Caloric restriction reprogramming of stress and reward neurocircuitry increases vulnerability to stress-induced binge eating"
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