Opponent-Process Theory: Welcome to the dark side

May 25 2009 Published by under Addiction, Neuroscience

You people. You people and your REQUESTS. Requests to do things like blog more about opponent-process theory. Well. Sci hears you. She obeys. At least this time. And for all your drug addiction experts out there asking me to read Koob, I can assure you that I have read a LOT of Koob in my time. For those of you not necessarily familiar with the drug abuse lit, George Koob is considered one of the greatest minds in current drug abuse research, and has done a lot to conform the motivationally-focused opponent-process theory to the model of drug addiction that exists today. Guy even has a wikipedia entry! That's how you know you've hit the big time.

ResearchBlogging.org And so, Sci continues her discussion of opponent-process theory in this second installment, with many thanks to Koob and his co-author, Le Moal.
Remember this?
OP Theory1.png
You'll need it.

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Things I like to Blog About: Addiction and the Opponent Process Theory

May 20 2009 Published by under Addiction, Neuroscience

Perhaps I should put a special category up for "things I like to blog about". Or maybe just 'basics'.
Sci's been a little out of her bloggin' groove lately, feelin' her stuff is not up to snuff. But with THIS, Sci will get her groove back. And she will get it back with pictures. Pictures that are drawn in powerpoint so they don't make your eyes bleed. I care.

So what is the opponent-process theory? The opponent-process theory (hereafter called the OP Theory) is one of the current theories we are using to understand addiction. Because, to be honest, we don't really understand it. Oh sure, we know about initial rewarding effects, we know about withdrawal, we know about tolerance. But do we really KNOW what it is that makes people walk away from their families and homes and jobs and sell themselves for their next hit? A next hit that, oftentimes, they HATE and need at the same time? ...nope. Still working on that.

But one of the theories out there to explain drug addiction and how it may work is the OP Theory.

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